Protection against H5N1 Avian Influenza Virus in Ducks

نویسندگان

  • Jinxiong Liu
  • Pucheng Chen
  • Yongping Jiang
  • Li Wu
  • Xianying Zeng
  • Guobin Tian
  • Jinying Ge
  • Yoshihiro Kawaoka
  • Zhigao Bu
  • Hualan Chen
چکیده

6 1 State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, CAAS, 7 427 Maduan Street, Harbin 150001, P. R. China 8 2 Institute of Medical Science, University of Tokyo, Tokyo 108-8639, Japan 9 3 ERATO Infection-Induced Host Responses Project, Saitama 332-0012, Japan 10 4 Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, 11 USA 12

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Waterfowl represent the natural reservoir of all subtypes of influenza A viruses, including H5N1. Ducks are especially considered major contributors to the spread of H5N1 influenza A viruses because they exhibit diversity in morbidity and mortality. Therefore, as a preventive strategy against endemic as well as pandemic influenza, it is important to reduce the spread of H5N1 influenza A viruses...

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Control measures for H5N1 avian influenza involve increased biosecurity, monitoring, surveillance and vaccination. Subclinical infection in farmed ducks is important for virus persistence. In major duck rearing countries, homologous H5N1 vaccines are being used in ducks, so sero-surveillance using H5- or N1-specific antibody testing cannot identify infected flocks. An alternative is to include ...

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تاریخ انتشار 2011